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P450芳香化酶与多囊卵巢综合征 被引量:2

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摘要 P450芳香化酶是雄激素转化为雌激素的限速酶,其表达具有组织特异性,在不同的组织中转化不同的底物,产生不同活性的雌激素,P450的表达受多种调节因子的作用,多囊卵巢综合征患者卵巢中P450芳香化酶的表达异常的,造成卵巢激素分泌紊乱,影响卵泡成熟和排卵,但是多囊卵巢综合征妇女卵巢中芳香化酶的表达缺陷还是亢进尚无定论,寻找调节P450芳香化酶的特异蛋白也是未来的研究方向之一,就P450芳香化酶在多囊卵巢综合征中的表达及影响因素作综述。
作者 田君 丘彦
出处 《国际生殖健康/计划生育杂志》 CAS 2008年第1期40-42,共3页 Journal of International Reproductive Health/Family Planning
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参考文献20

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同被引文献25

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  • 10洪琴,曲军英.芳香化酶改变在多囊卵巢综合征发病中的作用[J].国际生殖健康/计划生育杂志,2009,28(2):121-123. 被引量:5

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