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PGE2及其EP3受体在PAG脑区参与炎性疼痛的调节 被引量：4

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摘要 目的检测炎性疼痛大鼠PAG脑区PGE2浓度及EP3受体的表达。方法大鼠左后爪注射CFA诱导炎性疼痛模型,微量透析技术收集PAG脑区透析液,应用酶联免疫试剂盒检测透析液PGE2浓度,免疫组化结合抗体荧光标记观察EP3受体表达。结果炎性疼痛组PAG脑区透析液PGE2浓度较对照组高四倍,免疫组化见EP3受体表达明显增强。结论PAG脑区PGE2及其EP3受体参与炎性疼痛的调节。
作者 吕牮 李佳睿 刘铜军
机构地区 吉林大学第一医院
出处 《中国老年学杂志》 CAS CSCD 北大核心 2008年第2期126-128,共3页 Chinese Journal of Gerontology
关键词 前列腺素E2 中脑导水管周围灰质区 炎性疼痛
分类号 R338.22 [医药卫生—人体生理学]
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参考文献15

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共引文献4

同被引文献66

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中国老年学杂志
2008年 第2期

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