摘要
讨论了非水毛细管电泳(NACE)的优势和缺点,分别评价了常用非水溶剂作为运行介质的潜力,非水介质中电渗流的产生原因与控制机理。对于NACE的分离机理,尤其是静电相互作用与疏溶剂相互作用对分离的影响进行了讨论。着重评述了NACE在电中性物质的分离以及离子对手性拆分方面的应用及其机制。
A review on the content described in the article was given in this paper, relating especially to the topics on the merits and demerits of non-aqueous capillary electrophoresis （NACE） ; the significant potentialities of several commonly used organic solvents employed as running mediums; the reason of producing electro-osmosis and principle on its control; and on the mechanism of separation by NACE, particularly on the effects of electrostatic and solvophobic interactions on the separation of neutral and chiral compounds.
出处
《理化检验（化学分册）》
CAS
CSCD
北大核心
2008年第1期90-95,共6页
Physical Testing and Chemical Analysis(Part B:Chemical Analysis)
基金
国家自然科学基金(20375051,20775096)
教育部高校青年教师奖(教人司[2002]123)
重庆大学研究生教育创新基金(2004A007)
关键词
非水毛细管电泳
分离
静电相互作用
疏溶剂相互作用
电中性及手性化合物
Non-aqueous capillary electrophoresis
Separation
Electrostatic interaction
Solvophobic interaction
Neutral and Chiral compounds
