可逆性后部白质脑病综合征

Reversible Posterior Leukoencephalopathy Synodrome

可逆性后部白质脑病综合征的病因较为复杂,发病机制存在许多争论,临床表现为头痛、恶心、呕吐、癎性发作、意识障碍和视觉异常,神经影像学检查显示以双侧大脑后部为主的大片对称性白质水肿,经过及时有效的治疗临床症状和影像学改变均可完全恢复。如果延误治疗,也可并发脑梗死或脑出血,导致不可逆性脑损伤。

The etiology of reversible posterior leukoencephalopathy syndrome （RPLS） is more complex. Its pathogenesis has a lot of controversies, and its clinical manifestations are headache, nausea, vomiting, epileptic seizure, consciousness disturbance and visual abnormality. Neuroimaging examinations have shown that diffuse symmetrical white matter edema is predominantly in the bilateral posterior brain regions. Clinical symptoms and neuroimaging changes can be recovered completely after timely and effective treatment. If the treatment is delayed, it may compli- cate with cerebral infarction or hemorrhage, and lead to irreversible damage.