块状珊瑚兔颅骨骨膜下种植

Subperiosteal implantation of block coral on the rabbit cavarial bone

为观察珊瑚人工骨在皮质骨表面的骨传导作用，将块状珊瑚植入兔一侧颅骨骨膜下，另一侧为空白对照组，分别于术后２、４、８及１２周时处死动物，进行光镜、扫描电镜及组织形态测量学观察。结果显示：珊瑚植入颅骨表面２周时即有新骨向珊瑚孔内长入，珊瑚被进行性吸收；１２周时珊瑚块大部分被吸收，新骨改建成板层骨，新骨所修复的骨高度较珊瑚块的高度低，珊瑚组新骨修复的骨高度明显大于空白对照组。结论：珊瑚骨在皮质骨表面有良好的骨传导作用。

The aim of this study was to evaluate osteoconductive effect of coral implanted on surface of the cortical bone. The 2mm thick block corals were implanted on the surface of one side of rabbits cavarial bone, the another side were used as blank control. The specimen was examined by light microscopy, histometry and scanning electron microscopy at 2, 4, 8, 12 weeks after operation respectively. The results show that the new bone growth into the pore of the coral at 2 weeks after implantation. The coral was progressively absorbed and replaced by new bone. Up to 12 weeks, most of the coral was absorbed and newly formed bone had been remodeled. The reconstructed height of new bone in coral group was significantly higher than that of blank control and lower than the thickness of block coral. The study demonstrated good osteoconductive property of coral implanted on surface of cortical bone.