摘要
作者前瞻性调查了230例危重病患者,根据危重病患者全身性炎症反应综合征(SIRS)和多器官功能障碍综合征(MODS)的症状,分析SIRS到MODS的渐进发展过程,探讨治疗策略。结果显示:患者转入加强医疗病房(ICU)时,SIRS患病率71.3%,病死率18.9%。230例患者中,65例发生MODS(28.3%),死亡33例(50.8%)。非感染性SIRS、全身性感染及感染性休克患者的MODS患病率依次为22.8%,61.1%和85.7%,而病死率依次为11.4%,30.6%和50.0%。作者认为,早期诊断SIRS,并积极调控机体炎症反应,可能是改善危重患者预后的关键。
We defined the epidemiology of systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS) in critically ill patients, and evaluated the procession from SIRS to MODS and the therapeutic strategies.230 patients were studied prospectively until discharge or death.On admission,the morbidity rate of SIRS was 71 3%. The mortality rate of the patients with SIRS was 18 9%.MODS was developed in 65 patients (28 3%), and 33 patients dided (50 8%). In SIRS patients with non infectious SIRS, sepsis and septic shock, the morbidity rates of MODS were 22 8%, 61 1% and 85 7%, and the mortality rates were 11 4%, 30 6% and 50 0% respectively. The outcome of critically ill patients may be improved if SIRS is early diagnosed and the body inflammatory response is reglulated properly.
出处
《中华外科杂志》
CAS
CSCD
北大核心
1997年第7期402-405,共4页
Chinese Journal of Surgery