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高效液相层析测定单唾液酸四己糖神经节苷脂钠含量方法的研究 被引量:1

STUDIES ON QUANTITATIVE DETERMINATION OF MONOSIALOTETRAHEXOSYL GANGLIOSIDE SODIUM WITH HPLC
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摘要 目的:研究高效液相层析测定单唾液酸四己糖神经节苷脂钠含量的方法。方法:对照比较了C18柱、NH2柱和C8柱三种测定方法。结果:研究显示C18反相高效液相层析具有较好的鉴别实验专属性。结论:选择C18柱测定法为稳定性指示分析方法和有关物质和降解产物检查方法较为合理。 Objective: To study the determination of monosialotetrahexosyl ganglioside sodium with the method of HPLC. Methods:To compare three kinds of methods of C18, NH2, and C8 column. Resuits:Manifestation of RP- HPLC -C18 method has exclusive property in identifying experiments. Conclusion:So choosing this method to be the stability designation analysis method and relevant material check method are more reasonable.
作者 张小宁
出处 《内蒙古医学院学报》 2007年第6期411-415,共5页 Acta Academiae Medicinae Neimongol
关键词 高效液相层析 含量测定 单唾液酸四己糖神经节苷脂钠 HPLC quantitative determination monosialotetrahexosyl ganglioside sodium
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