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上皮间质转化在肿瘤侵袭转移中的作用 被引量:10

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摘要 上皮间质转化(epithelial-mesenchymal transitions,EMT)与肿瘤的侵袭转移密切相关,涉及多个信号通路和复杂的分子机制。参与这一过程的信号通路有TGF-β信号途径、PI3K/AKT途径、受体酪氨酸激酶Ras-MAPK途径、WNT信号途径等,研究其在肿瘤侵袭转移中的发生发展机制,从而为阻断肿瘤转移提供新的有效的靶点。
出处 《实用肿瘤杂志》 CAS 2008年第1期86-90,共5页 Journal of Practical Oncology
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