疏肝健脾法对考试前应激状态相关电位的影响

The Affect of Regulating Liver and Tonifying Spleen on the Event Related Potential under the Stress State Before Examination

目的:探讨疏肝健脾的中药制剂对考试前应激状态的调理作用及机理。方法:选取12名参加2007年硕士研究生考试的大四学生,随机分成中药组和对照组,两组进行考试焦虑自评量表、POMS量表、事件相关电位ERP测定。结果:中药组与对照组相比,考试焦虑量表服药前与考试前的差值、考试前与考试后的差值有显著性差异,POSM量表的TMD计分服药前与考试前的差值有显著性差异、在Fz、Pz、CPz电极点的P300的潜伏期考试前与考试后的差值有显著性差异,对照组与中药组相关电位P300的振幅考试前、考试后组间及差值均没有显著性差异。结论:疏肝健脾的中药对考试前应激状态的焦虑与心境状态有一定的调理作用、对考试前应激状态的认知功能有一定调理作用,可以缩短事件相关电位(ERP)P300潜伏期在考试前后的差值。

Objective： To observe the regulating action of the herbs with the function of Regulating Liver and Tonifying Spleen on the stress state before examination and study its possible mechanism. Method： Twelve undergraduate students who taking part in the entrance examination for postgraduate students in 2007 were randomly divided into the treatment group received the treatment of herbs and the control group All the samples were assessed by the Examination Anxiety Self - assament Scale, POMS Scale and received the examination of Event Related Potential （ERP）. Results： There are obvious differences between the scores of Examination Anxiety Self- assament Scale of before taking herbs and before examination, and the scores of before and after the examination in the treatment group. And there is also an obvious difference between the scores of TMD of POSM Scale of before taking herbs and before the examination. There are significant differences of the difference values of the incubation periods of P300 at the electrode points of Fz, Pz and CPz before and after the examination between the treatment and the control groups. While the difference values of the amplitude of P300 before and after the examination have not any differences between the two groups. Conclusion： The herbs of Regulating Liver and Tonifying Spleen have a certain action on the regulating the anxiety of stress state before examination; the herbs of Regulating Liver and Tonifying Spleen have a certain effect on the cognition of stress state before examination, which can shorten the differences values of the incubation periods of P300 of ERP before and after the examination.