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肾小管上皮细胞转分化的信号转导途径 被引量:1

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摘要 肾小管间质纤维化是各种慢性肾脏疾病进展为终末期肾功能衰竭的共同途径。近年来研究发现,肾小管上皮细胞转分化(tubular epithelial to mesenchymal transdifferentiation,TEMT)是肾小管间质纤维化发生和进展的重要机制。多种生长因子、细胞因子、激素和细胞外某些因素,
出处 《泸州医学院学报》 2008年第1期98-100,共3页 Journal of Luzhou Medical College
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  • 1Qi w, Chen X, PolhiU TS, et al. TGF-β1 induces IL-8 and MCP-1 through a connective tissue growth factor-independent pathway[J]. Am J Physiol Renal Physiol,2006 290(3): 703
  • 2Mishra R, Zhu L, Eckert R.L, et al.TGF-β-regulated collagen type Ⅰ accumulation: role of Src-based signals[J].Am J Physiol Cell Physiol,2007; 292(4): 1361
  • 3Strutz F, Okada H, Lo CW, et al. Identification and characterization ofa fibroblast marker: FSP1 [J]. J Cell Biol,1995; 130(2): 393
  • 4Strutz F, Muller GA. Transdifferenfiation comes of age[J]. Nephrol Dial Transplant,2000;15(11): 1729
  • 5Yang J, Liu Y. Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis[J]. Am J Pathol,2001;159(4):1465
  • 6Kalluril R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis[J].J Clin Invest,2003;112(12): 1776
  • 7Bottinger EP,Bitzer M.TGF-beta signaling in renal disease [J].J Am Soc Nephrol,2002;13(10):2600
  • 8Inman GJ, Nicolas El, Hill CS.Nucleocytoplasrnic shuttling of Smad2,3 and Smad4 permits sensing of TGF-beta receptor activity[J].Mol Cell,2002;10(2):283
  • 9Shi Y, Massague J. Mechanisms of TGF-β signaling from cell membrane to the nucleus[J].Cell,2003; 113(6): 685
  • 10Li Y, Yang J, Dai C,et al.Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis[J].J Clin Invest,2003;112(4): 503

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