1[1]Maeda N.DNA polymorphisms in the controlling region of the human haptoglobin genes:a molecular explanation for the haptogtobin 2-1 modified phenotype[J].Am J Hum Genet,1991,49(1):158-166.
2[2]Langlois MR,Delanghe JR.Biological and clinical significance of haptoglobin polymorphism in humans[J].Clin Chem,1996,42(10):1589-1600.
3[3]Maeda N,Yang F,Barnett DR,et al.Duplication within the haptoglobin Hp2 gene[J].Nature,1984,309(5964):131-135.
4[4]Asleh R,Marsh S,Shilkrut M,et.al Genetically determined heterogeneity in hemoglobin scavenging and susceptibility to diabetic cardiovascular disease[J].Circ Res,20(13,92(11):1193-1200.
6[6]Lavie L,Lotan R,Hochberg I,et al.Haptoglobin polymorphism is a risk factor for cardiovascular disease in patients with obstructive sleep apnea syndrome[J].Sleep,2003,26(5):592-595.
7[7]Levy AP,Hochberg I,Jablonski K,et al.Haptoglobin phenotype is an independent risk factor for cardiovascular disease in individuals with diabetes:the strong heart study[J].J Am Coll Cardiol,2002,40(11):1984-1990.
8[8]Levy AP,Levy JE,Kalet-Litman S,et al.Haptoglobin genotype is a determinant of iron,lipid peroxidation,and macrophage accumulation in the atherosclerotic plaque[J].Arteriosler Thromb Vase Biol,2007,27 (1):134-140.
9[9]Suleiman M,Aronson D,Asleh R,et al.Haptoglobin polymorphism predicts 30-day mortalityand heart failure in patients with diabetes and acute myocardial infarction[J].Diabetes,2005,54(9):2802-2806.
10[10]Blum S,Asaf R,Guetta J,et al.Haptoglobin genotype determines myocardial infarct size in diabetic mice[J].J Am Coll Cardiol,2007,49(1):82-87.
5Polonovski M,Jayle MF. Existence dans leplasma sanguin d'une substance aetivant l'act peroxydasique de l'am hemoglobine[J]. Comptes Rendus des Seances de la Societe de t3iologie et de Ses Filiales, 1938,129(2) : 457-460.
6Nielsen MJ,Petersen SV, Jacobsen C, et al. A unique loop exten- sion in the serine protease domain of haptoglobin is essential for CD163 recognition of the haptoglobin-hemoglobin complex[J]. J Biol Chem,2007,282(7) :1072-1079.
7Carter K, Worwood M. Haptoglobin: a review of the major allele frequencies worldwide and their association with diseases[J]. Int JLab Hematol,2007,29(8) :92-110.
8Atkinson SH, Mwangi TW, Uyoga SM, et al. The haptoglobin 2-2 genotype is associated with a reduced incidence of Plasmodium fal- ciparum malaria in children on the coast of Kenya[J]. Clin Infect Dis,2007,44(1) :802-809.
9Cox SE, Doherty C, Atkinson SH, et al. Haplotype association be- tween haptoglobin(Hp2)and Hp promoter SNP(A-61C) may ex- plain previous controversy of haptoglobin and malaria protection [J]. PloS ONE,2007,2(1) :e362.
10Buehler PW,Abraham B,Vallelian F,et al. Haptoglobin preserves the CD163 hemoglobin scavenger pathway by shielding hemoglo bin from peroxidative modification [J]. Blood, 2009, 113 ( 10 ) : 2578-2586.
