摘要
在对桔梗总皂苷粗分的基础上，利用制备高效液相色谱分离制备桔梗单体皂苷，共分离得到四个化合物，经波谱法分别鉴定为platycodinD（1），platycoside E（2），deapio-platycoside E（3），未知化合物（4，鉴定中），经HPLC分析，纯度均大于98％．对比以前的分离手段，该方法分离制备桔梗单体皂苷工艺简单，效率高，为在桔梗中寻找新的天然活性物质提供了新方法。
On the basis of separation for phatycodins,the saponins were separated and prepared by HPLC. Four saponins were obtained and they were identified as platycodin D （1）, platycoside E （2）, deapio-platycoside E （3）, anol unknown compound（4,identlfying） by spectrum respectively. The purity of them quantitated by HPLC was above the 98%. This method for separating and preparing the platycodin is a simple artwork and very effficient,which provided a new way for seeking active compounds from the roots of Platycodon grandiflorum.
出处
《天然产物研究与开发》
CAS
CSCD
2007年第B08期326-327,332,共3页
Natural Product Research and Development
基金
吉林省科技厅基金项目（20040207-1-2）
