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脑电双频指数和听觉诱发电位指数监测在吸入麻醉中的应用比较

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摘要 目的:观察腹腔镜胆囊切除术(LC)中异氟醚吸入维持麻醉期间听觉诱发电位指数(AAI)和脑电双频指数(BIS)在麻醉深度监测中的作用。观察吸入麻醉下BIS、AEP和血流动力学的变化,评估这两种监测方法在吸入麻醉中的应用价值。方法:60例ASAI级择期行LC的患者,随机分为AAI和BIS两组,每组30例,行常规静脉诱导全麻,持续吸入异氟醚维持,并调整吸入末浓度为1.0MAC、1.5MAC,每一浓度维持15分钟,分别记录基础值(T1)、气管插管时(T2)、气腹后(T3)、1.0MAC时(T4)、1.5MAC时(T5)和气管拨管(T6)六个时间点MAP、HR、AAI、BIS值。结果:T1-T6各时点比较,麻醉诱导插管后AAI、BIS值有显著的下降(P<0.05)手术结束拔管后(T6)AAI、BIS也明显升高,但较诱导前基础值为低,两者比较有差异性(P<0.05)。T3时点为气腹后BIS、AAI值都有上升,随着异氟醚呼末浓度的升高AAI、BIS值明显下降(P<0.05),T5较T4有明显下降(P<0.05)。MAP、HR诱导后下降,在T3时明显升高(P<0.05),在呼末异氟醚浓度为1.5MAC(T5)时下降,但T4较T5比较无统计学意义。AAI和BIS都与异氟醚吸入浓度有很好的相关性,而与MAP、HR无好的相关性。结论:结合BIS、AAI监测可更全面的反映麻醉深度。
出处 《新疆医学》 2008年第1期1-4,共4页 Xinjiang Medical Journal
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