需血运重建的女性早发冠心病患者临床特点与预后情况

Clinical features and prognosis of female premature coronary artery disease who needed coronary revascularization

目的比较需血运重建的早发冠心病患者临床特点与预后情况的性别差异。方法回顾性分析需血运重建的早发冠心病患者临床资料，观察终点事件与二级预防情况。结果3763例患者中，女性797例（21．2％）。其中早发冠心病123例，占女性患者的15．4％；男性早发冠心病患者387例，占男性患者的13．0％。与男性相比，女性早发冠心病患者既往心肌梗死史或因急性心肌梗死入院的比例小。男性患者吸烟比例较大，而女性患者有高血压病史的较多，血脂异常、肥胖或超重在男性患者更为显著。女性患者前降支病变的比例高，血运重建方式不存在性别差异，更多的女性患者达到完全血运重建。终点事件无显著性别差异。结论女性早发冠心病患者的危险因素及血管病变与男性存在差异。

Objective To compare the sex difference of clinical features and prognosis of premature coronary artery disease （CAD） who needed coronary revaseularization. Methods The clinical data of premature CAD who needed coronary revaseularization were analyzed retrospectively. The end-point event and secondary prevention were observed. Results The study population included 3763 individuals ： 797 female （ 21.2% ） , of whom female premature CAD was found in 123 （ 15.4% ） ,and male premature CAD in 387 （ 13.0% ）. Fewer female patients had perior myocardial infarction or admitted with acute myocardial infarction. Sex difference existed in the risk factors for premature CAD ： more male patients smoked, but more female had a history of hypertention. Hyperlipidemia and obesity or overweight were more significant in male patients. More female patients had lesions of LAD. There was no sex difference in the methods of coronary revaseularization. More female patients had got complete revaseularization. And no sex difference existed in end-point event. Conclusion The risk factors of female patients with premature coronary artery disease and vascular lesions are different from the male＇s.