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血脂康联合阿托伐他汀治疗对急性冠脉综合征患者血脂及高敏C反应蛋白的影响 被引量:5

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摘要 目的观察血脂康和阿托伐他汀联合治疗对急性冠脉综合征(ACS)患者高敏C反应蛋白(hsCRP)和血脂的影响。方法将116例ACS患者随机分为2组:A组予血脂康和阿托伐他汀联合治疗,B组予阿托伐他汀治疗,入院时及治疗6个月后测血清hsCRP、血脂(TC、TG、LDL-C、HDL-C)水平。结果治疗6个月后2组患者血清hsCRP、TC、LDL-C水平均较入院时降低,A组较B组改善更明显(P<0.05);A组HDL-C较入院时升高(P<0.05)。结论血脂康和阿托伐他汀联合治疗ACS可有效降低血清hsCRP水平,改善血脂水平。
作者 王岩
出处 《现代中西医结合杂志》 CAS 2008年第7期998-999,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
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参考文献6

  • 1ACC/AHA Guidelines for the management of patients with unstable angina and non ST segment elevation myocardial infarction. A report of American college cardiology/American heart association task force for partition guidelines[J ]. J Am Coll Cardiol,2002,36: 970- 1026
  • 2Fuster V, Badimon JL, Master P, et al. The pathogenesis of coronary artery syndromes[J]. N Eng J Med, 1992,326 ; 1014 - 1016
  • 3Frederic AL. Markers of inflammation as predictors in cardiovascular diseases[J]. Clin Chem Acra,2000,293:31 - 52
  • 4Laufs U, Fata VL, Plutzky J,et al. Upregnlation of endothelial nitric oxide synthase by HMG- CoA reductase inhibitors[J].Circulation, 1998,97 : 1129 - 1135
  • 5郑晓伟,曾定尹,王晓静,陈燕,邢福琴,石玉秀,李建华.血脂康对高脂饮食家兔血管内皮细胞功能的保护作用[J].中华内科杂志,1998,37(6):367-370. 被引量:31
  • 6赵水平.急性冠状动脉综合征患者应尽早服用他汀类药物[J].中华心血管病杂志,2004,32(11):961-962. 被引量:81

二级参考文献10

  • 1李中言,中华心血管病杂志,1996年,24卷,73页
  • 2Stenestrand U, Wallentin L. Early statin treatment following acute myocardial infarction and 1-year survival. JAMA,2001,288:430-436.
  • 3Thompso PT. Clinical relevance of statins: instituting treatment early in caute coronary syndrome patients. Atherosclerosis, 2001, 2 Suppl:15-19.
  • 4Aronow HD, Topol EJ, Roe MT, et al. Effects of lipid-lowering therpay on early mortality after acute coronary syndromes: an observational study. Lancet, 2001, 357:1063-1068.
  • 5Spencer FA, Allegrone J, Goldberg RJ, et al. Association of statin therapy with outcomes of acute coronary syndrome: The GRACE study. Ann Intern Med, 2004, 140:857-866.
  • 6Schwartz GG, Olsson AG, Ezekowitz MD, et al. Effects of atorvastain on early recurrent ischemic events in acute ccoronary syndromes: the MIRACLE study. Arandomized controlled trial. JAMA, 2001, 285:1711-1718.
  • 7Cannon CP, I Braunwald E, McCabe C, et al. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med, 2004, 350:1495-504.
  • 8de Lemos JA,Blazing MA,Wiviott SD et al. Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes.JAMA, 2004, 292:1307-1316.
  • 9Nissen SE. High-dose statins in acute coronary syndromes.Not just lipid levels. JAMA, 2004, l 292:1365-1367.
  • 10Grundy SM, Cleeman JI, Merz NB, et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. Circulation, 2004, 110:227-239.

共引文献110

同被引文献36

  • 1姜兵.浅谈血脂康的临床应用进展[J].基层医学论坛,2012,16(S1):89-90. 被引量:3
  • 2路一平,邱健.阿托伐他汀对鼠糖尿病动脉粥样硬化主动脉组织因子表达的影响[J].实用医学杂志,2006,22(9):998-1000. 被引量:4
  • 3王权.高脂血症的中医辨证分型及临床应用体会[J].贵州医药,2006,30(7):664-665. 被引量:6
  • 4潘晓冬,王绿娅,刘舒,杜兰萍.血脂康对高脂血症患者小而密低密度脂蛋白的影响[J].中国临床药理学与治疗学,2007,12(6):714-717. 被引量:1
  • 5Zhou T, Zhou S H, Qi S S, et al. The effect of atorvastatin on serum myeloperoxidase and CRP levels in patients with acute coronary syndrome [ J ]. Clin Chim Acta, 2006,368 (1-2) : 168-172.
  • 6Ray K K, Cannon C P. The potential relevance of the multiple lipid- independent (pleiotropic) effects of statins in the management of acute coronary syndromes [J]. J Am Coll Cardiol, 2005,46(8) : 1425-1433.
  • 7Kinlay S, Schwartz G G, Olsson A G, et al. Inflammation, statin therapy, and risk of stroke after an acute coronary syndrome in the MIRACL study [J]. Arterioscler Thromb Vasc Biol, 2008,28 ( 1 ) : 142-147.
  • 8Kanadasi M, Cayli M, Demirtas M, et al. The effect of early statin treatment on inflammation and cardiac events in acute coronary syndrome patients with low-density lipoprotein cholesterol [J]. Heart Vessels, 2006,21 (5) : 291-297.
  • 9Choudhry N K, Levin R, Winkelmayer W C. Statins in elderly patients with acute coronary syndrome : an analysis of dose and class effects in typical practice [ J ]. Heart, 2007,93 (8) : 945-951.
  • 10Leu H B, Lin C P, Lin W T, et al. Circulating mononuclear superoxide production and inflammatory markers for long-term prognosis in patients with cardiac syndrome X [J]. Free Radic Biol Med, 2006,40(6) :983-991.

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