脑内微出血在急性脑梗死后出血中的临床意义

The Effects of Microbleed in the Cerebral Bleeding after Acute Cerebral Infarction

目的研究脑内微出血(cerebral microbleed,CMB)在急性脑梗死患者急性期发生出血转换中的临床意义。方法连续收集急性脑梗死住院患者260例,通过磁共振梯度回波T2*加权成像(gradient-echoT2*-Weighted imaging,GRE-T2*WI)评价CMB严重程度。结果260例脑梗死患者中,伴CMB的占28.1%;伴CMB的脑梗死患者一周内脑出血的发生率高于不伴CMB的患者(P<0.01);年龄和CMB是脑梗死患者急性期发生出脑出血的独立危险因素。结论CMB能增加脑梗死后出血的可能性,对伴有CMB的脑梗死患者,应注意预防脑出血的发生。

Objective To assess the impact of cerebral microbleed （CMB） on the occurrence of cerebral bleeding（CB） after cerebral infarction （CI）. Methods We consecutively recruited 260 patients with acute cerebral infarction, gradient-echo T2^＊-Weighted imaging （GRE-T2＊WI） was performed to appraise the serious degree of CMB when admitted. Results For 260 patients with CI, the frequency of CMB in acute cerebral infarction patients was 28.1%. The occurrence of CB in patients with CMB is higher than those without CMB （P〈0.01）.CMB and age were leading influence risk factors for the CB. Results CMB may increase the possibility of CB occurrence, we should prevent the occurence of CB in the patients of CI with CMB.