思茅引种催吐萝芙木的化学成分研究

Study of the Chemical Constituents of Rauvolfia Vomitoria Afzel

从加纳引种思茅的催吐萝芙木(Rauvolfia vomitoriaAfzel)根的乙醇提取物分别在pH=2和pH=9时,用氯仿萃取,从中得到了14个化合物,经波谱分析鉴定为:α-onocerin(1)、methyl 3,4,5-trimethoxycinnamate(2)、betulinic acid(3)、3β,22E,22S-stigmasta-5,22-dien-3-O-β-D-glucopyranoside(4)、loganic acid(5)、7,2′-O-diacetylloganic acid(6)、mitoridine(7)、10,11-dimethoxy-α-yohimbine(8)、isoreserpiline(9)、19-epiajmalicine(10)、10,11-dimethoxy-19-epiajmalicine(11)、reserpine(12)、poke-weed cerebroside(13)、β-sitoterol(14)。其中化合物1、2、3、4、6、13为首次从该属植物中分离得到。

The ethanol extract of the root of Rauvolfia vornitoria Afzel, introduced from Ghana and cultivated in Simao Jiangcheng County of Yunnan Province,was extracted with CHCl3 at pH = 2 and pH = 9.14 compounds were isolated from two fractions and identified on the basis of their spectral data as α-onocerin （ 1 ）, methyl 3,4,5-trimethoxycinnamate （2）, betulinic acid （3）, 3β,22E, 22S-stigmasta- 5,22-dien-3-O-β-D-glucopyranoside （ 4 ）, loganic acid （ 5 ）, 7, 2＇-O-diacetyl loganic acid （ 6 ）, mitoridine （ 7）, 10,11 -dimethoxy-α-yohimbine （8）, isoreserpiline （ 9 ）, 19-epiajmalicine （ 10）, 10,11- dimethoxy-19-epiajmalicine （ 11 ）, reserpine （12）, poke-weed cerebroside （13） and β-sitoterol （14）. Compounds 1, 2, 3, 4, 6 and 13 were first isolated from this genus.