偶发分枝杆菌肉芽肿与结核性肉芽肿巨细胞形态学定量研究

Comparison of Histomorpho-metric Differences in Giant cells Between Granulomas of Mycobacterium Fortuitum(MF) and Tuberculosis

目的:探讨巨细胞形态学定量分析在皮肤软组织偶发分枝杆菌(MF)肉芽肿和结核性肉芽肿中的诊断与鉴别诊断价值。方法:选择MF肉芽肿和结核性肉芽肿患者各10例进行组织病理学观察,并应用计算机形态计量学分析方法对组织切片中的巨细胞参数进行测定。结果:MF肉芽肿的形态学及巨细胞参数与结核性肉芽肿的巨细胞有所不同。结论:结合临床病理特点及巨细胞形态计量学检测,对MF肉芽肿和结核性肉芽肿的诊断与鉴别诊断有一定价值。

Objective ：To explore the value in diagnosis and differential diagnosis of quantitative evaluation of morphology of Giant cells in granulomas of Mycobacterium fortuitum（MF） and tuberculosis. Methods ：Morphological observations were done and Morphological index of giant cells in granulomas of MF and tuberculosis were investigated using Motic medical digital image analysis system. （Motic Med 6.0）. Results：The pathologic features and morphological index of giant cells of the granulomas of MF were different from which of the granulomas in tuberculosis. Conclusion：The correct diagnosis can be carried out in granulomas of MF and tuberculosis according to the clinical and pathologic characteristics and the quantitative evaluation of morphology of Giant cells in granulomas.