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血管内皮细胞生长因子与急性肺损伤 被引量：4

Vascular endothdial growth factor and acute lung injury
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摘要 小儿急性肺损伤（ALI）及ALI的严重形式急性呼吸窘迫综合征的主要病理特征是弥漫性肺泡-毛细血管壁损伤。血管内皮细胞生长因子（VEGF）可以促进肺泡细胞、血管内皮细胞增殖，也可以提高血管通透性。因此，VEGF可能成为一种反映ALI病理和（或）肺损伤及修复状况的生物学指标。该文对VEGF及其受体的基本生物学特性、VEGF与ALI相关的动物及临床研究作一综述。
作者 宋俊峰(综述) 孙波(审校)
机构地区 复旦大学附属儿科医院
出处 《国际儿科学杂志》 2008年第1期22-25,共4页 International Journal of Pediatrics
关键词 血管生成因子 急性呼吸窘迫综合征 急性肺损伤 细胞生长
分类号 R735.7 [医药卫生—肿瘤] R725.6 [医药卫生—儿科]
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参考文献23

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同被引文献79

  • 1陈玉君,刘唐威,陈克正.血管内皮生长因子在急性肺损伤中的促炎作用[J].中国小儿急救医学,2006,13(5):480-481. 被引量：5
  • 2杨宗城.吸人性损伤//杨宗城.烧伤治疗学.3版.北京:人民卫生出版社,2006:360.
  • 3McCarter SD, Mei SH, Lai PF, et al. Cell-based angiopoietin- lgene therapy for acute lung injury. Am J Respir Crit Care Med, 2007,175 (10) : 1014-1026.
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  • 6Lee JW, Fang X, Krasnodembskaya A, et al. Concise review: mesenchymal stem cells for acute lung injury: role of paracrine soluble factors. Stem Ceils, 2011,29(6) :913-919.
  • 7Mei SH, McCarter SD, Deng Y, et al. Prevention of LPS-in- duced acute lung injury in mice by mesenchymal stem ceils over expressing angiopoietln 1. PLos Med, 2007,4 (9) : e269.
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国际儿科学杂志
2008年 第1期

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