新生儿高未结合胆红素血症83例临床分析

Clinical Analysis of Neonatal Unconjugated Hyperbilirubinemia in 83 Newborns

目的探讨新生儿高未结合胆红素血症(高胆)的临床特征。方法对83例新生儿高胆临床资料进行分析总结。结果83例高胆中,男54例,女29例。感染因素42例,围生因素24例,母乳因素13例,溶血因素4例。肝功能损害26例,心肌损害10例。结论感染因素是新生儿高胆的最常见原因,其次是围生因素、母乳因素及溶血因素。部分病例可引起多脏器损害。蓝光照射治疗效果好,是降低高胆的主要手段。

Objective To explore the clinical characteristics of neonatal unconjugated hyperbilirubinemia. Methods The clinical materials of 83 newborns with neonatal unconjugated hyperbilirubinemia were analyzed and summarized. Results In all 83 cases（54 male,29 female）,42 cases were caused by infection factors,24 cases by perinatal factors, 13 cases by breast-feeding and 4 case by hemolytic disease. The main complications were liver function damage （26 cases） and cardiac muscle damage （ 10 cases ）. Conclusions So the infection factors were the most common causes of unconjugated hyperbilirubinemia in the newborns, and perinatal factors, breast-feeding and hemolytic disease of newborn followed. Some cases were combined with complications. Phototherapy was effective to reduce the level of bilirubin in the treatment of unconjugated hyperbilirubinemia in the newborns.