摘要
溶血和血栓是目前国内心室辅助装置不能应用于临床的主要原因。血泵的不良血液动力学特性是导致溶血和血栓的主要因数。计算流体力学(CFD)方法目前被广泛应用于血泵设计,它可以准确有效地反映血泵内部流场状态、血泵压力流量曲线以及血泵内部流场剪切力分布状态等。本研究采用CFD方法对自制螺旋血泵的泵腔、出入流口进行流场分析,内部流场采用三维彩图显示。结果显示CFD分析结果很好的与体外实验结果吻合。血泵血液动力学特性,以及内部血流状态采用CFD方法分析,可以有效地分析血泵血液相溶性方面的问题。
A low rate of thrombus formation and hemolysis is an important factor for the development of a rotary blood pump. Poor fluid dynamic characteristics of blood flow arc main factors that cause thrombus formation and hemolysis, Some essays demonstrate that CFD is a convenient and effective approach to analyze the behavior of blood in a heart assist device, CFD modelings are widely used for predicting prcssurc-flow curves, hydraulic efficiencies and scalar fluid stress levels of LVAS. In this study, we evaluated a motor-driven nonpulsatile left ventricular assist device （LVAD） by means of CFD. The blood pump chamber （stroke volume 76mL） and the inflow and outflow port were evaluated by CFD analysis. We adopted thrce-dimensional distribution of CFD results for inner blood flow state qualitative evaluation, The computed prcssurc-flow characteristics of the pump were in good agreement with the measurements, CFD offers a convenient tool for the general assessment of prcssurc-flow performance, fluid force estimation and blood damage level in the flow domain,
出处
《中国生物医学工程学报》
CAS
CSCD
北大核心
2008年第1期93-96,共4页
Chinese Journal of Biomedical Engineering
基金
国家高技术研究发展863计划(2006AAO2Z4E8)
