摘要
Objective： To explore the characteristic of operation, intra-operation treatment and the application of immunosuppressant in pediatric renal transplantation in order to improve therapeutic effectiveness. Methods： From March 1986 to October 2006, the clinical data of 63 children who underwent renal transplantation in our hospital were retrospectively analyzed. Results： The 1-, 3-, 5-, 10-year graft survival rates were 98.4%, 90.5%, 88.9% and 68.3%, respectively. And the corresponding patient survival rates were 100%, 95.2%, 92.1%, 71.4%. The body weight increased 4 to 12 kg and the body height grew up 2 to 6 cm during the first year post-transplantation. The main complications in the first year post-transplantation were hypertension （26/63, 41.3%）, crinosity （14/63, 22.2%）, drug-induced hepatic injury（11/63, 17.5%）, gingival hyperplasia （10/63, 15.8%）, pulmonary infection（9/63, 14.3%）, bone marrow suppression（5/63, 7.9%）, herpes （4/63, 6.3%） and diabetes （3/63, 4.8%）. Conclusion： Renal transplantation is a preferred method for the treatment of children in end-stage renal disease （ESRD）. Good tissue matching, proper operative time and pattern, peri-operactive care were essential to success, as well as appropriate immuno-suppressant strategy and good compliance.
ObjectiveTo 在小儿科的肾的移植探索操作，intra操作治疗和抑制免疫力的药的申请的特征以便改进治疗学的 effectiveness.MethodsFrom 1986年3月到2006年10月，在我们的医院里经历了肾的移植的 63 个孩子的临床的数据是回顾地 analyzed.ResultsThe 1-，3-，5-，10年的接枝幸存率分别地是98.4%，90.5%，88.9%和68.3%。并且相应耐心的幸存率是 100% ， 95.2% ， 92.1% ， 71.4% 。体重增加了 4 ～ 12 kg，身高长大了 2 ～ 6 厘米在第一年期间移植以后。第一年里的主要复杂并发症移植以后是高血压( 26/63 ，41.3%)，多毛( 14/63 ，22.2%)，导致药的肝的损害( 11/63 ，17.5%)，齿龈的增生( 10/63 ，15.8%)，肺的感染( 9/63 ，14.3%)，骨髓抑制( 5/63 ，7.9%)，疱疹( 4/63 ，6.3%)并且糖尿病( 3/63 ，4.8%) .ConclusionRenal 移植是为在结束阶段的孩子的治疗的一个比较喜欢的方法肾的疾病( ESRD )。匹配的好织物，合适的起作用的时间和模式， peri-operactive 照顾对成功，以及适当抑制免疫力的药策略和好依从必要。
