数字X线机骨密度测量的实验和临床应用

Experimental and clinical application of DR bone mineral densitometry

目的通过骨标本实验测量和临床测定，验证数字X线机骨密度测量系统的准确性和性能。方法利用数字X线机及XBMS测量软件，采用标准体模，测定离体骨标本20个，测量了骨矿含量（面密度），并与骨的单位面积重量，单位面积灰重相比较。采用同样技术测量正常体检对象的前臂远端骨矿含量，共425例（男218例，女207例），进行了分年龄组统计，并找出男女骨峰值，初步制定了临床诊断标准。结果离体骨骨矿含量与单位面积重量呈显著正相关，r=0．8713，P〈0．01；与单位面积灰重呈显著正相关，r=0．9032，P〈0．01。临床检查表明男女前臂远端骨矿含量峰值均在30～39岁组[男（1．039±0．127）g／cm^2；女（0．848±0．093）g／cm^2]，峰值以后随年龄逐渐降低。结论实验和临床测定证实，数字X线机骨密度测量系统测量的骨矿含量与骨的单位面积重量和单位面积灰重具有良好的相关性。

Objective To determine the accuracy and precision of X-ray Bone Mineral Measurement System （XBMS） by experiment and evaluate the performance by clinical application. Method the bone mineral content （BMC） of 20 bone samples in vitro were measured using DR and XBMS. Compare the BMC with bone area specific gravity and bone ash area specific gravity. Measuring the BMC of distal end of Radius and Ulna of 425 cases（218 male and 207 female）. The means and standard deviations of BMC are calculated by age groups. The top value of BMC is obtained in men and women. The clinical diagnosis standard is established. Result The data of sample experiment shows that BMC is significantly positive correlated with bone （ r = 0.8713, P 〈 0.01 ） and bone ash weight per area specific gravity （ r = 0.9032, P 〈 0.01 ）. The result of clinical examination shows that the BMC of distal end of Radius and Ulna decrease with growing age. The top value of BMC are at age group of 30 -39 years[ （1.039 ± 0.127）g/cm^2 in men; （0.848 ±0.093） g/cm^2 in women]. Conclusion The experiment confirmed that the XBMS has good accuracy and precision. The technique is sensitive. The operation is simple. The method can be easily popularized.