摘要
Recent progress made in many biological sciences such as genomics, genetics, and molecular biology has made molecular targeting possible. Although thousands of disease-causing molecules（genes and proteins alike） can theoretically be drug targets, there have been limited cases with successful drag targets that have been moved to clinical practice. Advances in experimental biomedical research have provided many sophisticated methods that can improve our ability to link human diseases with specific genes or proteins and to explore the underlying mechanisms. However, these approaches have not bee well validated for drag targeting. This presentation aims at providing a systemic review on the state-of-art information and technology in the field of drag targeting and its role in the process of drag discovery and drug development. After a brief discussion of the process of modem drag discovery and development, the roles of drag targeting in drug discovery, design, development, and delivery will be reviewed.
Recent progress made in many biological sciences such as genomics, genetics, and molecular biology has made molecular targeting possible. Although thousands of disease-causing molecules（genes and proteins alike） can theoretically be drug targets, there have been limited cases with successful drag targets that have been moved to clinical practice. Advances in experimental biomedical research have provided many sophisticated methods that can improve our ability to link human diseases with specific genes or proteins and to explore the underlying mechanisms. However, these approaches have not bee well validated for drag targeting. This presentation aims at providing a systemic review on the state-of-art information and technology in the field of drag targeting and its role in the process of drag discovery and drug development. After a brief discussion of the process of modem drag discovery and development, the roles of drag targeting in drug discovery, design, development, and delivery will be reviewed.
