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磺化聚醚砜对光敏剂-亚甲蓝的吸附去除研究Ⅱ.磺化聚醚砜对血浆中亚甲蓝的吸附去除研究

Study on Adsorption of Methylene Blue by Sulfonated Polyethersulfone Ⅱ.The Adsorption of Methylene Blue by Sulfonated Polyethersulfone in Plasma
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摘要 研究了磺化聚醚砜吸附柱对血浆中亚甲蓝的吸附效果,并检测了流经吸附柱的牛血清白蛋白随时间变化的规律以及过柱前后血浆中主要生化指标的变化情况。结果:磺化聚醚砜对亚甲蓝的吸附效果明显优于聚醚砜对亚甲蓝的吸附效果;其对白蛋白的吸附较小;对血浆中主要生化指标的影响可以忽略不计。 The evaluation of the adsorption of methylene blue (MB) in plasma by sulfonated polyethersulfone (SPES) adsorbent column was carried out in this study. The results indicated the adsorption of MB by SPES adsorbent column was more efficient than that by polyethersulfone (PES). In addition, the changes of the concentration of BSA solution passing through adsorbent column along with the time and the biochemical indices of plasma before and after adsorption treatment were also investigated. The results showed that the adsorption amount of BSA by PES adsorbent column was larger than that by SPES, and the biochemical parameters such as total protein, albumin, glucose, triglyceride and total cholesterol in plasma varied slightly before and after passing through the column, which were still within the clinical indices.
出处 《生物医学工程学杂志》 EI CAS CSCD 北大核心 2008年第1期135-138,共4页 Journal of Biomedical Engineering
关键词 聚醚砜 磺化聚醚砜 亚甲蓝 吸附 牛血清白蛋白 Polyethersulfone (PES) Sulfonated polyethersulfone ( SPES ) Methylene blue ( MB ) Adsorption Bovine serum albumin(BSA)
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  • 1Lunn G, Sanaone EB. Decontamination of aqueous solutions of biological stains. Biotechnic & Histochemistry, 1991; 66:307
  • 2Elena K, Giulo J. Review of chem. Intermediates, 1988; 10:260
  • 3Gutter B, Nishioka Y, Speck WT, et al. Immunofluorescence for the detection of photo-chemical lesions in intracellular DNA. Exptl Cell Res, 1976; 102:413
  • 4Troche BI. The methylene blue baby. N Eng J Med, 1989; 320: 1756

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