厚朴温中丸中厚朴酚与和厚朴酚含量测定的研究

Studies on Content Measuring of Magnolol and Honokiol in Magnoliae Officinalis Pill

建立了厚朴温中丸中厚朴酚与和厚朴酚的含量测定方法。方法：采用HPLC测定厚朴酚与和厚朴酚的含量。结果：厚朴酚与厚朴酚含量测定方法的线性范围分别为0.488-2.440μg（Ch i-Square：27.44）和0.362-1.810μg（Ch i-Square：36.07）,平均回收率分别为97.0%,RSD=1.3%（n=5）和96.8%,RSD=1.4%（n=5）。结论：所建立的方法准确可行,重复性好,可作为厚朴温中丸中控制厚朴含量的质量标准。

The method of measuring the content of magnolol and honokiol in Magnoliae Officinalis Pen is established. Method： Adopting HPLC to measure the content of magnolol and honlkiol. Result ：The linear scope of measuring method of content of magnolol and honokiol is 0. 488 -2.440μg（ Chi - Square：27.44） and 0. 362 - 1. 810μg（ Chi - Square： 36.07） respectively. The average recovery ratio is 97.0%, RSD = 1.3% （ n = 5 ） and 96.8%, RSD = 1.4% （ n = 5 ） respectively. Conclusion ：The method established is accurate and practical with good repeatability. It can be taken as the quality norm for controlling the content of officinal magnolia bark in Magnoliae Officinalis Pill.