期刊文献+

成年小型猪脑电图正常模式的研究 被引量:1

The electroencephalogram and brain electrical activity mapping patterns in Chinese experimental mini pigs
下载PDF
导出
摘要 目的:为获得中国实验小型猪(CEMP)正常脑电图参考数据。方法:麻醉下,对CEMP行头皮电极描记额叶、颞叶、顶叶、枕叶的脑电图(EEG)波型并进行了两两样本间的t检验分析。结果:麻醉状态下CEMP的EEG模式以δ波为主,其时间指数为44%~75%,θ波时间指数为5%~32%,并经二次处理得出其脑电地形图(BEAM)。结论:CEMP具有可以重复描记出的脑电活动,故可以将其用于神经系统疾病模型的研究,本实验研究结果可以作为该动物麻醉状态下的正常脑电活动的参考。 Objective: To acquire normal patterns of EEG in Chinese experimental mini pigs (CEMP). Methods: The EEGs at anesthetic state were recorded in 27 CEMPs. Results: The normal patterns of EEG in CEMPs at anesthetic state were similar to the humanity during sleep. Conclusions: The CEMP owns normal and recordable electric activity in the brain, so they are candidates for the neuroscience study.
出处 《临床神经电生理学杂志》 2008年第1期14-16,共3页 Journal of Clinical Electroneurophysiology
基金 首都医学发展基金资助研究项目2003-2016
关键词 中国实验小型猪 麻醉 脑电图 脑电地形图 Chinese experimental mini pig(CEMP) Anesthesia Electroencephalogram(EEG), Brain electrical activity mapping(BEAM)
  • 相关文献

参考文献7

  • 1裴德智.简述中国实验用小型猪[J].实验动物科学与管理,1997,14(1):36-37. 被引量:13
  • 2Stromberg MW, Kitchell RL, UsenikEA, et al. Electrocorticographic Patterns in Normal Pigs and Burros[J]. Am J Vet Res, 1962,23(95) :737-743.
  • 3魏泓.我国小型猪研究的现状[J].中国实验动物学杂志,1997,7(4):252-255. 被引量:25
  • 4张文莉,王士雯,徐斌,黄丽洁,苟鹏,高磊,李泱,高伟.中国小型猪阻塞型睡眠呼吸暂停模型的建立[J].中国比较医学杂志,2004,14(5):286-289. 被引量:22
  • 5Drenthen J, van Hulst RA, blok JH, et al. Quantitative EEG Monitoring During Cerebral Air Embolism and Hyperbaric Oxygen treatment in a pig model[J]. Neuropsychopharmacology, 2006,31 : 925-932.
  • 6Kalisch RSchubert M. Jacob W,et al ,Anxiety and Hippocampus volume in the Rat[J]. Neuropsychopharmacology, 2006, 31:925-932.
  • 7Darling BK,Abdel-Rahim M, Moores RR, et al. Brain Excitatory Amino Acid Concentrations are Lower in the Neonatal Pig: A Buffer against Excitotoxicity? [J]. Biol Neonate, 2001,80:305-312.

二级参考文献6

  • 1Ariel T, Steven M. Cardiovascular effects of periodic obstructive and central apneas in dogs[J]. Am J Respir Crit Care Med, 1994, 150:83 - 89.
  • 2Fleetham JA. Is sleep disordered breathing associated with increased morbidity[ J] ? Thorax, 1998, 53: 627 - 628.
  • 3Kimoff, John R, Hideo M, et al. Canine model of obstructive sleep apnea: model description and preliminary application [J]. J Appl Physiol, 1994, 76: 1810- 1817.
  • 4Weil JV, Cherniack NS, Dempsey JA, et al. Respiratory disorders of sleep. Pathophysiology, clinical implications, and therapeutic approaches[J]. Am Rev Respir Dis, 1987, 136:755 - 761.
  • 5Hendricks JC, Kline LR, Kovalski RJ, et al. The English bulldog:a natural model of sleep-disordered breathing [ J ]. J Appl Physiol,1987, 63: 1344- 1350.
  • 6Wissler RW.Updme on the pathogenesis of atherosclerosis[J].Am J Med,1991,91(Suppl):S1-S35.

共引文献54

同被引文献2

引证文献1

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部