BIS监测技术在儿童结肠镜检查中的应用

Clinical study on bispectral index monitoring used for no pain-anesthesia during fibercolonoscopy in children

目的探讨在儿童纤维结肠镜检查中使用脑电双频指数(BIS)、95%边缘频率(95%SEF)监测丙泊酚全凭静脉麻醉深度的可行性。方法50例10岁以下儿童予丙泊酚3mg/kg静脉诱导,8mg/(kg·h)维持。记录入室时(T1)、入镜时(T2)、通过脾区(T3)、停丙泊酚输入(T4)、退镜时(T5)、患儿有体动、睁眼时(T6)的BP、HR、SpO2、BIS及95%边缘频率(95%SEF)的变化;记录麻醉诱导到入镜的时间、停止丙泊酚输入到有体动、睁眼的时间。结果BP、HR、BIS、95%SEF在T2时明显下降,与T1相比差异有显著性(P<0.05)。T6的BP、HR、SEF、BIS与T1时相比差异无显著性。结论BIS可以指导、监测患儿的麻醉镇静深度。丙泊酚持续静脉泵入可满足儿童内镜手术的麻醉要求,达到理想的麻醉效果。

[Objective] To monitor propoful anesthetic depth by bispectral index （BIS） and 95% spetral edge frequency （95% SEF） during fibereolonoscopy in children. [Methods] Propoful anesthesia were induced in fifty children under 10 years old with at a dose of 3 mg/kg and maintained at 8mg/kg·h continuous intravenous infusion. Blood pressure （BP）, heart rate （FIR）, pulse oxygen saturation （SpO2）, BIS and 95%SEF were measured before operation（T1）, fiberoscope inserted（T2）, passing through spleen flexure（T3）, propoful infusion stopped（T4）, fiberoscope taken out（T5）, body moving and eye opening（T6）. [Results] Bp, HR, BIS and 95% SEF at T2 were decreased significantly compared with data at T1 （P 〈0.05）. There was no difference between T1 with T6. [Conclusion] BIS can predict the anesthetic depth. Propoful is a suitable agent for induction and maintenance during fibercolonoscopy in children.