离子表面活性剂胶团对阿斯匹林碱水解反应的影响

Inhibition of Basic Hydrolysis Reaction of Aspirin by Micelles of Ionic Surfactants

离子表面活性剂胶团对阿斯匹林碱水解反应的影响史振民＊刘生昆张祝莲巩育军（延安大学化学系延安７１６０００）关键词表面活性剂，阿斯匹林，碱水解反应，胶团，抑制作用１９９６－０５－０４收稿，１９９６－０８－１２修回阿斯匹林（ＡＳＰ），学名为乙酰水杨酸，有较...

Cetyltrimethylammonium bromide (CTAB) and sodium dodecyl sulfate (SDS) were used as surfactants and effects of micelles on the basic hydrolysis of aspirin (ASP) were studied spectrophotometrically. When the concentrations of CTAB are larger than 7 3×10 -3 mol/L, there is an inhibition of basic hydrolysis of ASP, the best concentration being 3 25×10 -3 mol/L. At a constant concentration of CTAB, the addition of a small amount of SDS causes the inhibition of CTAB to decrease, indicating that SDS takes part together with CTAB in the formation of mixed micelles.