摘要
By the reactlon of (substituted silyl )methanethiols with 1-chloromethyl-2, 8, 9-tri-oxa- 5-aza-1-silabicyclo [3. 3, 3] undecane, eleven novel organosilicon compounds were syn-thesized. Their structures were confirmed by 1H NMR, MS and elementary analysis. A rare rearrangement breakdown pattern was found ln their mass spectra. Preliminary bioassay re-sults showed these compounds have some antitumor activity.
By the reactlon of (substituted silyl )methanethiols with 1-chloromethyl-2, 8, 9-tri-oxa- 5-aza-1-silabicyclo [3. 3, 3] undecane, eleven novel organosilicon compounds were syn-thesized. Their structures were confirmed by 1H NMR, MS and elementary analysis. A rare rearrangement breakdown pattern was found ln their mass spectra. Preliminary bioassay re-sults showed these compounds have some antitumor activity.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1997年第1期76-78,共3页
Chemical Journal of Chinese Universities
基金
国家自然科学基金重点基金
关键词
有机硅化合物
合成
生物活性
Organosilicon compound
Synthesis
Bioactivity
