糖尿病患者血清微量元素测定的临床意义

Clinical significance of serum trace elements determination in patients with diabetes mellitus

目的通过检测糖尿病患者血清中微量元素的含量,探讨微量元素对糖尿病的影响。方法对40例糖尿病患者和51例健康人血清锌(Zn)、铜(Cu)、镁(Mg)、钙(Ca)定量测定。结果糖尿病组血清Zn、Mg、Ca明显低于健康对照组(P<0.01或P<0.05),Cu明显高于对照组(P<0.01),差异有统计学意义。结论本研究提示糖尿病患者体内存在Zn、Cu、Mg、Ca代谢紊乱,检测其血清中微量元素的变化对病情估计及治疗有一定的临床意义。

Objective To detect the content of serum trace Elements in patients with diabetes mellitus,and therefore to investigate the effect of trace elements on diabetes mellitus. Methods Serum zinc,copper, magnesium and calcium were quantitatively determined in 40 patients with diabetes mellitus （DM group） and 51 healthy people （control group）. Results The contents of serum zinc,magnesium,and calcium in DM group were significantly lower than those of control group （P〈0.01 or P〈0.05） ,while serum copper content higher than that of control group （P 〈0. 01）. The differences were statistically significant. Conclusion There exist metabolic disorders of zinc, copper, magnesium and calcium in the body of patients with diabetes mellitus. The determination of serum trance elements contributes to illness evaluation and treatment for diabetes mellitus.