三亚甲基碳酸酯和己内酯生物可降解共聚物序列结构的二维核磁分析

Two Dimensional Nuclear Magnetic Resonance Analysis on the Sequence Structure of Biodegradable Copolymer Derived from Trimethylene Carbonate and ε-Caprolactone

以辛酸亚锡[Sn(Oct)2]为催化剂、乙二醇为引发剂,通过本体开环共聚,合成了己内酯(CAP)与三亚甲基碳酸酯(TMC)的共聚物。采用1H、13C核磁共振及同核二维相关谱(gCOSY)、13C-1H异核相关谱(gHSQC)和13C-1H异核远程相关谱(gHMBC)等二维核磁共振(2D NMR)技术,对所合成的聚合物进行了序列微结构表征,找出了聚合物分子链中序列连接方式,并完成了1H和13C NMR谱带的归属。

The copolymers of ε-caprolactone （CAP） and trimethylene carbonate （ TMC ） were synthesized by ring-opening bulk copolymerization using stannous octoate [ Sn（Oct） 2 ] as catalyst and ethylene glycol as initiator. The sequence microstructures of the resulting copolymers were characterized by ^1H, ^13C nuclear magnetic resonance spectroscopy （ ^1H and ^13C NMR） and two-dimensional nuclear magnetic resonance （2D NMR） techniques including homonuclear correlation spectroscopy with gradient（gCOSY） , ^1H detected heteronuclear single quantum coherence with gradient（gHSQC ） and ^1H detected heteronuclear multiple-bond coherence with gradient（gHMBC） etc. The linkage modes of sequence in the copolymer chain were found. The assignments of all ^1H and ^13C bands for the copolymers were completed.