摘要
建立蒙成药萨拉吉德-11含量测定方法。采用HPLC法测定姜黄素的含量。色谱柱为Hypersil C18，流动相为乙腈-4%冰醋酸溶液（48：52），流速为1．0mL·min^-1，柱温为30℃，检测波长为430nm；姜黄素的线性范围为0．039072-0．19536μg，r=0．9995，平均加样回收率为100．8%，RSD=1．8％，该方法具有简便、快速、准确等特点，可用于萨拉吉德-11的质量控制。
A HPLC method was established for determination of Salajide-11. Hypersil G8 colunm was used with acetonitrile-4% acetic acid solution （48 ： 52） as mobile phase. The flow rate was 1.0 mL · min^-1 , colunm temerature was 30℃, and the detecting wavelength was 430nm. The Linear range was within 0. 039072-0. 19536μg （r=0. 9995）. The average recovery rate was 100.8% and RSD was 1.8% . The method is simple, rapid and accurate. It can be used in the quality control of Salajide-11.
出处
《中国药事》
CAS
2008年第2期139-140,共2页
Chinese Pharmaceutical Affairs
