抗CD20单克隆抗体在风湿性疾病治疗中的应用
摘要
随着对B细胞在风湿性疾病发病机制中作用的进一步认识，相应的生物靶向治疗应运而生。研究表明，抗CD20单克隆抗体（Rituximab），可有效治疗包括类风湿关节炎、系统性红斑狼疮、中性粒细胞胞浆抗体（ANCA）相关系统性血管炎、皮肌炎、冷球蛋白血症、慢性冷凝集素病、多发性硬化等多种难治性自身免疫性疾病。现就B淋巴细胞在风湿性疾病中的发病机制。Rituximab治疗风湿性疾病的疗效和安全性方面的研究进展综述如下。
出处
《北京医学》
CAS
2008年第2期114-116,共3页
Beijing Medical Journal
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共引文献3
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