二氢槲皮素曼尼希碱盐的制备及其抗氧化性能研究

Study on preparation and antioxidant activity of dihydroquercetin mannich salt

通过曼尼希反应由二氢槲皮素制备其衍生物——曼尼希碱盐,考察其对DPPH自由基清除能力及其在KI-H2O2体系和猪油中的抗氧化性能。通过实验证明,二氢槲皮素曼尼希碱盐常温下在水中的溶解度比二氢槲皮素大大提高,对DPPH自由基的清除能力比二氢槲皮素有所增加。在KI-H2O2体系中二氢槲皮素曼尼希碱盐的抗氧化能力比二氢槲皮素、槲皮素和抗坏血酸都要好,对猪油的抗氧化能力比二氢槲皮素弱,但是比BHT强。二氢槲皮素曼尼希碱盐在猪油中最佳添加量为2.0mmol/L。

Dihydroquercetin mannich salt was prepared by mannich reaction, and its ability to scavenge free radicals and antioxidant ability in KI-H2O2 system and lard were studied. The results showed that the solubility of dihydroquercetin mannich salt in water was better than dihydroquercetin. Its scavenging DPPH radicals ability was increased. Its antioxidant activity in KI-H2O2 system was better than dihydroquercetin, quercetin and Vc. Its antioxidant activity in lard was stronger than dihydroquercetin, but weaker than BHT. The optimal amount of dihydroquercetin mannich salt in lard was 2. 0mmol/L.