摘要
用超声的方法合成了纤维素三苯甲酸酯(CTB),并将得到的产物用红外光谱与元素分析进行了表征。将该种手性固定相(CSP)用于薄层色谱分离手性化合物,分别采用TEAA,乙腈∶TEAA=2∶1及乙酸乙酯∶水∶冰乙酸=6∶2∶1作为展开剂,使2-(9-蒽基)-2-甲氧基乙酸、2-(9-蒽基)-2-羟基乙酸及苯丙氨酸都获得了完全分离。
Tribenzoyl-cellulose was synthesized by homogeneous reaction of benzoyl chloride with microcrystalline cellulose in pyridine under ultrasonication at about 45℃. Elemental analysis and IR spectra indicated that almost all hydroxyl groups of the cellulose were converted to ester groups in the pure polymeric form. The prepared tribenzoyl-cellulose was used as chiral stationary phase of thin-layer chromatography to separate three chiral molecules, 2-(9-anththryl)-2-methoxyacetic acid, 2-(9-anthryl)- 2-hydroxyacetic acid and 2-amino-3-phenylpropanoic acid. The three chiral molecules were completely separated by using TEAA, acetonitrile-1 % TEAA (2 : 1 ) and ethyl acetate-H2O-acetic acid (6 : 2 : 1) as developer, respectively.
出处
《分析科学学报》
CAS
CSCD
2008年第1期25-28,共4页
Journal of Analytical Science
基金
教育部重点科学技术研究项目(No.105153)
关键词
纤维素三苯甲酸酯
薄层色谱
手性拆分
Tribenzoyl-cellulose
layer chromatography
Chiral separation