虫草及其无性型中的抗肿瘤细胞活性成分

Anti-tumor components from Cordyceps and their anamorph

较系统地总结了目前在虫草及其无性型中发现的抗肿瘤细胞活性成分。其中冬虫夏草、蛹虫草、大团囊虫草、单侧虫草、戴氏虫草和拟蛹虫草等虫草以及它们的无性型蛹拟青霉、细脚拟青霉、金龟子绿僵菌和球孢白僵菌等虫生真菌代谢物中抗肿瘤细胞活性成分,其结构包括多糖类、甾醇类、含氮化合物和杂环化合物等多个类型。

A review on structures of anticancer compounds from the Cordyceps and their anamorph was made in this article. The summarized Cordyceps included Cordyceps sinensis, Cordyceps militaris, Cordyceps ophioglossiodes, Cordyceps unilateralis, Cordyceps tail and Cordyceps pseudomilitaris and so on. The reviewed anamorph were focused on Paecilomyces militaris, Paecilomyces tenuipes, Metarhizium anisopliae and Beauveria bassiana etc. The summarized structures included polysaccharides, steroids, N-contalning compounds and O-containing heterocyclic compounds and so on.