妊娠期糖尿病不同治疗时机对母婴预后的临床研究

Impact of different treatment time in gestational diabetes mellitus on maternal and neonatal outcomes

目的探讨妊娠期糖尿病不同治疗时机对母婴预后的影响。方法回顾性分析本院2001年1月～2006年12月住院分娩的78例妊娠期糖尿病患者，其中51例在孕中期确诊为妊娠期糖尿病并给予治疗，27例未行孕期保健或孕中期血糖筛查，于孕34周后住院确诊妊娠期糖尿病，将两组的妊娠结局进行比较。结果妊娠期糖尿病孕34周前治疗组中妊娠期高血压疾病、羊水过多、伤口感染、早产儿、新生儿窒息、巨大儿分别为15．69％、7．84％、5、88％、13．73％、7、84％、19．61％，均低于34周后治疗组，分别为37．04％、29．63％、25．93％、33．33％、11．11％、22．22％。结论妊娠期糖尿病对母婴危害大。及早诊断和治疗，可减少母婴并发症。

Objective To investigate the impact of different treatment time in women with gestational diabetes mellitus on maternal and neonatal outcomes. Methods Data of 78 women with GDM from January 2001 to December 2006 were reviewed. 51 GDM women had been treated before 34 gestational weeks and the rest 27 GDM women hadn＇t. The impact on maternal and neonatal outcomes were compared between the two groups. Results In the earlier treated group the incidence of hypertensive disorder complicating pregnancy, hydramnios, wound infection, premature infant, neonatal asphyxia, fetal macrosomia, were 15. 69%, 7.84 %, 5.88%, 13. 73%, 7. 84 %, 19. 61 %, respectively. It was much lower as compared with the later treated group, 37. 04 %, 29.63%,25.93%,33.33%,11. 11%,22.22%,respectively. Conclusion Gestational diabetes mellitus does great harm to mother and infant. Diagnosing GDM and controlling blood glucose as early as possible can decrease the complications of mother and infant.