动态三维超声心动图多巴酚丁胺负荷试验中冠心病人左室容积变化和意义

THE ALTERATION OF LEFT VENTRICULAR VOLUME DURING DOBUTAMINE STRESS 3-DIMENSIONAL ECHOCARDIOGRAPHY IN PATIENTS WITH CORONARY ARTERY DISEASE AND ITS SIGNIFICANCE

目的评价多巴酚丁胺负荷试验（ＤＳＴ）中冠心病（ＣＡＤ）病人左室容积（ＬＶＶ）的变化及临床意义。方法ＤＳＴ采用分级负荷方法，ＬＶＶ用动态三维超声心动图（３－ＤＥ）测定，以同期检查的正常人作对照。结果ＤＳＴ中正常人和ＣＡＤ病人ＬＶＶ、每搏输出量（ＳＶ）和射血分数（ＥＦ）呈不同的变化趋势，节段性室壁运动异常（ＲＶＭＡ）发生情况明显不同。

Objective To evaluate the alteration and clinical significance of left ventricular volume (LVV) in patients with coronary artery disease (CAD) during dobutamine stress testing (DST).Methods Multi-stage DST and 3-dimensional echocardiography (3-DE) were performed in CAD patients (n=30) to calculate the LVV. The results were compared with those of the mormal (n=13).Results There were significant differences between the 2 groups in LVV and the indices of left venrticular function (LVF), such as stroke volume and ejection fraction. The incidence of regional ventricular motion abnormality (RVMA) showed significant difference between the 2 groups.Conclusion Dobutamine-stress 3-DE is a dependabil means to assess a patient's LVF and ischemic response,which are crucial in diagnosing CAD, guiding its treatment and predicting its prognosis.