注射型原位成型药物传递系统的研究现状

Development of injectable in situ forming drug delivery systems

注射型原位成型药物传递系统在近年来得到了广泛关注。注射型原位凝胶植入局部位置并使多聚物以半固体形式贮存药物，这种形式相比其它传统的给药方式具有很多优点。本文重点介绍了原位系统中原位沉淀凝胶的贮药机制，特性及其优缺点。

The scope of drug-dellvery systems has expanded significantly in recent years.These are injectable fluids that can be introduced into the body in a minimally invasive manner prior to solidifying or gelling within thedesired site.This manuscript focuses on the recent advancements in the area of in situ forming biodegradable polymeric drug-deliverysystems.