更年期综合征中医证候及证候要素分布特点的文献分析

Literature analyses on distribution characteristics of TCM syndromes and syndrome elements of menopausal syndrome

目的:探讨更年期综合征中医证候的临床分布规律,在此基础上提取证候要素,总结其分布规律。方法:查阅近20年来辨证治疗更年期综合征的中医文献资料,遵循循证医学的原则,将符合选择标准的文献(470篇)录入到EpiData2.0数据库,转化为SPSS 12.0数据库后,统计证候及证候要素出现的频次、百分比。结果:144个证候类型中出现频次排在前3位的证候是肝肾阴虚证、肾阴虚证、肾阳虚证。得到证候要素48个,其中病位类证候要素(19个)出现频次排在前3位的是肾、肝、心,病机、病性类证候要素(29个)出现频次排在前3位的是阴虚、阳虚、火。结论:对更年期综合征文献的证候研究反映了该病的复杂性,同时也反映由于辨证者的思维和方法不一,造成临床分型十分繁杂,而用证候要素更能简洁、灵活地反映疾病本质。

Objective： To probe into distribution on characteristics of T CM syndromes and syndromes elements of menopausal syndrome. Methods： The literature about menopausal syndrome in past 20 years were collected. The principle of evidence-based medicine was used to estabhsh the databank with EpiData2,0, and the literature meeting the enrolled criteria were recorded and checked, SPSS12.0 software was adopted to analyze frequency-times of syndromes and syndromes elements. Results： The top three syndromes are yin-deficiency of both liver and kidney, yindeficiency of kidney, yang-deficiency of kidney; The kidney, liver, and heart are the top three locations of syndromes elements; And yin-deficiency, yang-deficiency and fire are the top three pathogenesis types of syndromes elements. Conclusion： Distribution of TCM syndrome types of menopausal syndrome is scattered. It lead to clinical syndrome differentiation is complicated. Compared with it, syndrome elements can reflect the substance of disease more concise and active.