食管癌非手术放疗联合化疗研究进展

Nonsurgical chemoradiotherapy in esophageal cancer treatment

放疗和化疗联合治疗食管癌的方式包括同期放化疗、序贯放化疗等多种方式。国外已对各种综合治疗方案进行了研究，其中，同期放化疗的疗效得到肯定，已取代单纯放疗，成为不能手术的局部晚期食管癌的标准治疗方法。为进一步提高局控率及生存率，许多研究在此基础上采用加速超分割及三维立体适形的放疗技术，并取得初步结果。

The combination of radiotherapy and chemotherapy in esophageal cancer patients treatment, including concurrent chemoradiotherapy and sequential chemoradiotherapy, has been already studied by foreign scholars. Thereamong,the concurrent chemoradiotherapy has been approved effective and become a standard treatment for unresectable advanced esophageal carcinoma instead of simple radiotherapy. To improve the survival and local control rates of patients,many researches on late course accelerated hyperfractionated radiotherapy and chemotherapy, three-dimensional conformal radiotherapy and chemotherapy have been studied and made preliminary results.