山莨菪碱凝胶防治静脉滴注甘露醇局部疼痛的疗效观察

A study on effect to fanisodamine gel to prevent region pain induced by intervenous drop infusion of mannitol

目的探讨山莨菪碱凝胶对防治静脉滴注甘露醇引起局部疼痛的疗效。方法将200例静脉滴注甘露醇的患者随机分为观察组和对照组各100例。观察组在静脉滴注甘露醇前5～10min将山莨菪碱凝胶沿静脉走向均匀地涂擦于输液穿刺点上方的皮肤，对照组先不作任何处理，对在滴注甘露醇过程中出现局部疼痛者均予2％山莨菪碱凝胶外涂给予治疗。结果观察组出现局部疼痛者8例（8％），对照组70例（70％），两者比较（P〈0．01），差异有统计学意义。对出现局部疼痛的78例患者均予山莨菪碱凝胶外涂给予治疗后，显效66例，中效12例。结论2％山莨菪碱凝胶能有效防治静脉滴注甘露醇所致的局部疼痛，减轻静脉损伤。

Objective To examine the effect of fanisodamine gel to prevent region pain induced by intervenous drop infusion of mannitoL Methods 200 TBI eases with region pain induced by intervenous drop infusion of mannitol were divided into two groups： the study group （ 100 cases） and the control group （ 100 cases）. The study group received 2% fanisodamine gel external application along vein path on skin up pricking point to prevent region pain before 5 - 10 rain intervenous drop infusion of mannitol. The control group received 2% fanisodamine gel external application to cure region pain when intervenous drop infusion of mannitoL Results Compared with 70 cases with pain in the control group （70%）, there were 8 cases with pain in the study group （P 〈 0. 01 ） . Treated with fanisodamine gel external application, there were 70 cases greatly improved and 12 cases median - effect in 76 cases with pain after intervenous drop infusion of mannitol. Conclusion External application of 2% fanisodamine gel could prevention and cure region pain induced by intervenous drop infusion of mannitol effectively and relieve injury of vein.