摘要
目的探讨非甾体消炎药(NSAID)相关胃肠粘膜损伤的特点。方法应用胃镜连续观察166例上消化道出血的患者,根据是否服用NSAID分为NSAID组(1组)和非NSAID组(2组)。结果两组胃粘膜糜烂患者分别为57.9%、37.2%;胃溃疡30.8%和27.1%;十二指肠溃疡11.3%和35.7%,NSAID组胃溃疡患者(33例)中有21例为胃窦溃疡,占63.6%,胃体溃疡12例,占36.4%;而对照组(16例)中胃窦溃疡9例(56.3%),胃体溃疡7例(43.7%),统计学显示两组在构成比方面有显著性差异(P﹤0.01)。结论NSAID相关的胃肠粘膜损伤镜下有其特征性。
Objective To investigate the association between nonsteroidal anti-inflammatory drugs and gastreduedenal lesions by gastroscopy. Method Observe 166 patients consecutively by gastroscopy who were diagnosed upper alimentary tract hemorrhage. The patients were divided in NSAID-related and non-NSAID-related groups(group 1 and group 2) according to whether taking NSAID or not. Result According to the examination of gastroscopy, gastroduodenal lesions were divided into three types: acute erosive gastritis and gastic ulcer and duodenal ulcer. These kinds of patients accounted for 57.9% and 30.8% and 11.3% respectively in group 1. For group 2, it was 37.2% and 27.1% and 35.7%. Conclusion There are more typical manifestations in patients' gastroduodenal lesions who used NSAID.
出处
《医学信息》
2008年第3期377-378,共2页
Journal of Medical Information
关键词
非甾体消炎药
胃肠粘膜损伤
胃镜
Non-steroid anti-inflammatory drug(NSAID)
Gastroduodenal lesion
Gastroscopy