芩荑合剂雾化吸入对支气管哮喘气道慢性炎症的影响

Influence on the Chronic Airway Inflammation of Bronchial Asthma by Absorbing the Combination Inhalation of Qinyi Heji

目的探讨芩荑合剂雾化吸入治疗慢性支气管哮喘的作用机理,评价其疗效。方法采用随机分组方法,将慢性支气管哮喘患者分为中药芩荑合剂雾化吸入组和西药必可酮吸入组,治疗2个疗程后,观察各组症状体征积分变化、肺功能变化、痰及血嗜酸粒细胞变化情况。结果芩荑合剂雾化液能显著降低哮喘患者的症状体征积分,显著改善肺功能,降低痰及血中嗜酸性粒细胞。结论芩荑合剂具有解痉、平喘、抗炎、祛痰等作用,能有效拮抗哮喘患者气道的变态反应性炎症,改善患者的肺功能。

Objective To discuss the action mechanism for the treatment ot chronlc bronchlal asthma through the clinical observation of the combination inhalation of Qinyi Heji, then evaluate its therapeutic effect. Method Patients were divided into two groups, one absorbed the Chinese herbal medicine Qinyi Heji inhaler, and the other absorbed becotide. The variation of integral of symptom and sign, the lung function and the eosinophilic granulocytes in phlegm and blood were observed. Result The combination inhalation of Qinyi Heji can improve the integrals of symptoms and signs, the lung funcion remarkably, and lower the eosinophilic granulocytes in phlegm and blood. Conclusion The combination inhalation of Qinyi Heji can antispasm, antigasp, relieve the inflammation, disappear phlegm and so on. Absorbing the medicines can improve the symtom and sign, resists the airway abnormal inflammation of bronchial asthma, and improve lung function.