强心复脉颗粒对兔窦房结急性缺血损伤心电图的影响

Effect of Qiangxin Fumai Granule on ECG with Acute Ischemic Injury of Sinoatrial Node in Rabbit

目的观察强心复脉颗粒对家兔窦房结急性损伤模型的影响。方法选用实验家兔50只,分为5组,即模型对照组、强心复脉颗粒大剂量组、强心复脉颗粒中剂量组、强心复脉颗粒小剂量组、阿托品组。实验组给予强心复脉颗粒,阳性对照组给予阿托品。结果强心复脉颗粒可以提高心率,改善窦房结功能,使起搏频率增快,从异位心律变为窦性心律,从而改善家兔心肌缺血,促进心肌细胞的代谢。结论强心复脉颗粒有提高心率、改善心肌缺血的作用。

Objective To study the effect of Qiangxin Fumai Granule （QXFMG） on rabbits induced with acute injury of sinoatrial node. Method 50 rabbits were divided into five groups-control group, QXFMG low dose group, QXFMG middle dose group, QXFMG high dose group and atropine group. The group on experiment was given QXFMG, and the active control group was given atropine. Result QXFMG can raise the heart rates, improve the function of sinoatrial node, thus speed up pacing frequency, and cause the consersion of ectopic cardiac rhythm into sinus rhythm, and then improve the cardiac muscle ischemic of the rabbits and speed the metabolization of cardiac muscle cellular. Conclusion QXFMG has the effect of raising heart rates and improving the cardiac muscle ischemic.