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脂联素及其受体与胰岛素抵抗的研究进展 被引量：4

Progress about Relationship of Insulin Resistance with Adiponectin and its Receptors
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摘要 脂联素是来源于脂肪组织的脂肪因子之一,脂联素与胰岛素抵抗相关疾病,如肥胖、代谢综合征、2型糖尿病、动脉粥样硬化有关。脂联素受体介导了脂联素的各种生物学效应,脂联素基因多态性可能会影响脂联素的表达水平及其功能,研究脂联素基因多态性、脂联素受体可以更好地理解脂联素作用的分子机制。 Adiponectin is one of the adipoeytokines that is derived from adipose tissue. Adiponectin is related to some diseases associated with insulin resistance, merabolic syndrome, type 2 diabetes, and athcrosclerosis.. Its receptors mediate all kinds of biological function of adiponectin. Adiponectin gene polymorphism perhaps affects the expression and function of adiponectin. Studies about its gene polymorphism and receptor will be helpful to recognize the molecular mechanism of action of adiponectin.
作者 周瑞秀 王静 逄力男
机构地区 潍坊医学院内科学教研室
出处 《医学综述》 2008年第4期515-517,共3页 Medical Recapitulate
关键词 胰岛素抵抗 2型糖尿病 脂联素 脂联素受体 Insulin resistance Type2 diabetes mellitus Adiponectin Adiponectin receptors
分类号 R587.1 [医药卫生—内分泌]
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医学综述
2008年 第4期

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