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透明质酸结合蛋白1及其在肿瘤研究中的作用 被引量:3

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摘要 透明质酸结合蛋白1(hyaluronan binding protein1,HABP1)是透明质酸黏素(hyaladherin)家族中的一员,它能够特异性的与透明质酸结合,具有独特的晶体结构和多种生物学特性,在哺乳动物细胞内外均有表达,可以与多种细胞蛋白发生作用,是一种多功能蛋白,涉及介导细胞-细胞及细胞-基质问的黏附、细胞信号的转导、精子的成熟和运动等方面,近年来的研究发现HABP1在一些肿瘤组织中呈现异常表达,并参与某些肿瘤的转移和侵袭过程。
作者 雷利娜 王晶
出处 《实用肿瘤学杂志》 CAS 2008年第1期83-86,96,共5页 Practical Oncology Journal
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