小剂量肝素联合维生素K_1佐治婴幼儿重症支气管肺炎疗效观察

Treatment of serious bronchopneumonia in infants with the aid of low dose of heparin and vitamin K1

目的：观察小剂量肝素联合维生素K1佐治婴幼儿重症支气管肺炎疗效及副反应。方法：将42例重症支气管肺炎婴幼儿随机分为治疗组和对照组。除常规治疗方法外,治疗组每次用肝素0.3-0.5 mg/kg,维生素K1每次0.3-0.5 mg/kg,均每日2次,连用3天后改用每天1次,再用2天后停用,观察两组临床疗效及副反应。结果：治疗组和对照组总有效率分别为95.0%和86.4%,治疗组优于对照组（P〈0.05）,且治疗组未发现明显副反应。结论：小剂量肝素联合维生素K1佐治婴幼儿重症支气管肺炎临床效果好,副反应少,可以推广应用。

Objective：To study the clinical effects and side effects of low dose of heparin and Vitamin K1 intervention on serious bronchopneumonia in infants. Methods：Forty-two infants were randomly divided into therapeutic group and control group. In addition to the routine therapy,the theraneutycgroup was administered heparin 0.3 -0.5 mg/kg,vitamin K1 0.3 -0.5 mg/kg twice a day for three days, then once a day for two days;the control group received only the routine therapy. The curative effects and side reactions were observed. Results： The total effective rates of theraneutycgroup and control group were 95. 0% and 86. 4% , respectively. The theraneutycgroup was obviously superior to the control group （ P 〈 0.05 ） , and no obvious side reactions were observed. Conclusions： Treatment of serious bronchopneumonia in infants with the aid of low dose of Hepair and Vitamin K1 is effective and presents little side reaction. It is worth popularizing.