乳癖消巴布膏的刺激性、过敏性及经皮毒性研究

Study on the irritation,hypersensitiveness and percutaneous toxicity of Rupixiao patch

目的:考察乳癖消巴布膏皮肤用药的安全性。方法:用健康家兔分别进行完整与破损皮肤的皮肤刺激性试验;用健康豚鼠进行皮肤过敏试验;用健康大鼠进行慢性经皮毒性试验。结果与结论:乳癖消巴布膏对家兔无皮肤刺激性,对豚鼠无致敏性,对大鼠无经皮毒性。

Objective： To study the safety of Rupixiao patch. Methods：Skin irritation tests were carried on the integral and damaged skin of healht rabbits. The skin hypersensitive test and chronic percutaneous toxicity test were carried on guinea pigs and healthy rats. Results and Conclusion： lrritation,hypersensitiveness and toxicity didn＇t happened on the rabbits, guinea pigs and rats, respectively.